Is there any affect on renal perfusion, plasma levels of ace inhibitor or diuresis?
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Taken in combination, may lead to renal failure/decreased renal perfusion
Indapamide (marketed by Servier as Natrilix SR) is a thiazide-like diuretic. It inhibits Na/Cl reabsorption from the distal convulated tubules in the kidneys. It lower the blood pressure by inducing diuresis which means a fall in blood volume and decreasing on cardiac output. When taking for prolonged it causes lowering in peripheral resistance.
Indapamide may induces [...]